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- Title
l-Thyroxine induces thermotolerance in yeast.
- Authors
Papamichael, Konstantinos; Delitheos, Basil; Mourouzis, Iordanis; Pantos, Constantinos; Tiligada, Ekaterini
- Abstract
The cellular stress response (CSR) is a universal inducible reaction modulated, among others, by heat, drugs, and hormones. We aimed to investigate the role of l-thyroxine (T4) on the heat shock (HS) response in Saccharomyces cerevisiae. The CSR was evaluated by determining growth and viability of post-logarithmic phase grown yeast cultures after HS at 53 °C for 30 min. We found that long-term T4 exposure can induce a dose-dependent and Hsp90 and H+ trafficking-related thermotolerance in yeast.
- Subjects
YEAST culture; YEAST; SACCHAROMYCES cerevisiae; HEAT shock proteins; MECHANICAL shock measurement
- Publication
Cell Stress & Chaperones, 2019, Vol 24, Issue 2, p469
- ISSN
1355-8145
- Publication type
Article
- DOI
10.1007/s12192-019-00978-0