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- Title
Effects of chemical inducers on the Epstein-Barr virus cycle in epithelial/nasopharyngeal carcinoma hybrid cell line.
- Authors
Takimoto, T.; Ishiguro, H.; Umeda, R.; Ogura, H.; Hatano, M.
- Abstract
We have studied the induction of Epstein-Barr virus (EBV)-specific antigens in nasopharyngeal carcinoma hybrid cells by treatment with the tumor promotor 12-0-tetradecanoylphorbol-13-acetate (TPA), hydrogen peroxide (H2O2) and n-butyric acid. The intensity of EBV induction by these drugs was in the order of n-butyric acid----TPA----H2O2. Furthermore, the combination of H2O2 or TPA and n-butyric acid acted synergistically on EBV-induced antigens.
- Publication
ORL, 1984, Vol 46, Issue 4, p192
- ISSN
0301-1569
- Publication type
journal article
- DOI
10.1159/000275708