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- Title
Association Between Albumin-Bilirubin Score and Ventricular Arrhythmia in Patients with Heart Failure.
- Authors
Özilhan, Murat Oğuz; Açıkgöz, Sadık Kadri
- Abstract
Objectives: Heart failure (HF) is a serious disease associated with increased morbidity and mortality. Hepatic dysfunction secondary to hepatic congestion and ventricular arrhythmia (VA) are frequently observed in patients with HF. The albuminbilirubin (ALBI) score, which predicts liver damage, is a parameter that has been used in patients with HF in recent years. In this study, we investigated the predictive value of the ALBI score in detecting VA in patients with HF. Materials and Methods: This study was planned as a single-center retrospective study. The study included 150 consecutive HF patients with reduced ejection fraction who had an implantable cardioverter-defibrillator. The ALBI score was calculated using the following formula: [log10 TB (mg/dL) × 0.66] + [albumin (g/dL) × -0.085]. Patients were divided into two groups: those with and without VA. A receiver operator characteristic (ROC) curve analysis was used to define the cut-off level of the ALBI score to predict VA. Results: The mean age of the group was 55.3±10.8 years, and 78.7% of the patients were male. 28 patients (18.7%) had VAs. Male gender and HF hospitalization in the previous year were more common in the arrhythmia group. ALBI score was higher in the arrhythmia group (p<0.001). Sacubitril-valsartan and digoxin use were higher in the arrhythmia group, whereas beta-blocker and statin use were higher in the non-arrhythmia group. In multivariate logistic regression analysis, the ALBI score was found to be an independent predictor of VA. Male gender, hospitalization in the previous year, sacubitril-valsartan use, and digoxin use were other independent predictors of VA. ALBI score at a cut-off point of -3.66, predicts ventricular tachycardia with 74% sensitivity and 70% specificity in ROC curve analysis (area under the curve=0.732, p<0.001). Conclusion: The ALBI score is associated with VA in patients with HF. It can be easily assessed and used as a predictor of VA in this patient group.
- Subjects
ALBUMINS; VENTRICULAR arrhythmia; HEART failure; TACHYCARDIA; ENTRESTO
- Publication
E Journal of Cardiovascular Medicine, 2024, Vol 12, Issue 1, p17
- ISSN
2147-1924
- Publication type
Article
- DOI
10.32596/ejcm.galenos.2024.2024-6-60