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- Title
Signalling change: signal transduction through the decades.
- Authors
Hynes, Nancy E.; Ingham, Philip W.; Lim, Wendell A.; Marshall, Christopher J.; Massagué, Joan; Pawson, Tony
- Abstract
The past few years have marked significant anniversaries in signal transduction, including the identification of classic growth factors and morphogens, the notion of protein modification through phosphorylation and the characterization of protein interaction domains. Here, six researchers reflect on the context in which these discoveries were made, and how our concept of cell signalling has evolved during the past three decades.
- Subjects
CELLULAR signal transduction; MORPHOGENESIS; PHOSPHORYLATION; PROTEIN-protein interactions; CHEMICAL reactions; MICROBIAL genetics
- Publication
Nature Reviews Molecular Cell Biology, 2013, Vol 14, Issue 6, p393
- ISSN
1471-0072
- Publication type
Article
- DOI
10.1038/nrm3581