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- Title
تحضير وتشخيص بعض من مركبات ) 3,1 - اوكسازبين و 3,1 - بنزوكسازبين -7,4 ثنائي اون( المشتقة من السلفامثوكسازول باستخدام طريقة التشعيع وتقييم فعاليتها ضد البكتريا .
- Authors
فؤاد احمد عمر; أياد سليمان حمد; نهاد اسماعيل طه
- Abstract
In this study, new compounds of Schiff bases were prepared (1-6), from the reaction of sulfamethoxazole with benzaldehyde derivatives. Schiff bases (1-6) converted to 1,3-Oxazepine-4,7-dione and 1,3-Benzooxazepine-4,7-dione derivatives (7-18) through the reaction of Schiff bases with maleic anhydride as well as phthalic anhydride using crushing, grinding and microwave irradiation method. The structures of all prepared compounds have been identified by (I.R) technique, also some of the prepared compounds have been identified by (1H-NMR,13C-NMR) techniques. The biological activities have been carried out for some compounds such as (9,10,11,12,13,14,15,16,17) against two types of bacteria such as Staphylococcus aureus and Esherichia coil.
- Subjects
MALEIC anhydride; SCHIFF bases; PHTHALIC anhydride; STAPHYLOCOCCUS aureus; SULFAMETHOXAZOLE
- Publication
Kirkuk University Journal for Scientific Studies, 2022, Vol 17, Issue 2, p27
- ISSN
1992-0849
- Publication type
Article
- DOI
10.32894/kujss.2022.131552.1048