We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
FINDINGS ON PHYSICAL ACTIVITY --INFLUENCE ON TELOMERE SHORTENING.
- Authors
RĂCHITĂ, Carmen
- Abstract
Physical activity and increased physical fitness are known to decrease the likelihood of morbidity and mortality from a variety of causes (reduced cardiovascular disease, insulin resistance and hypertension), with concomitant increases in longevity. Telomere length is a primary biomarker of cellular aging that has recently been associated with cardiovascular disease, insulin resistance and hypertension, and morbidity and mortality. This is because as telomeres shorten, there is more stress on bodys tissues to function correctly. Researchers believe that exercise helps reduce damage by free radicals, allowing your body to invest its resources in maintaining health instead of repairing damage. Normal cells, after a finite number of mitotic divisions, they stop growing or they simply die. This happens mostly because of the shortening of telomeres (specialized chromosomal ends). Telomeres are biological aging markers, found in all living cells, with the major purpose of protecting chromosomes. In other words, these are DNA packages placed at the chromosomal, ends, preventing them from disintegration and delaying the process of aging. Once we get older, our telomeres shorten, cells become unprotected and they eventually die. It is said that telomeres shorten with 21 nucleotides per year.
- Subjects
PHYSICAL activity; PHYSICAL fitness; TELOMERES; GENETICS of longevity; CARDIOVASCULAR disease related mortality; CARDIOVASCULAR disease prevention; INSULIN resistance
- Publication
Discobolul - Physical Education, Sport & Kinetotherapy Journal, 2017, Vol 13, Issue 48, p94
- ISSN
1454-3907
- Publication type
Article