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- Title
Pulp revascularization of replanted immature dog teeth after treatment with minocycline and doxycycline assessed by laser Doppler flowmetry, radiography, and histology.
- Authors
Ritter, Alessandra Luisa de Souza; Ritter, André Vicente; Murrah, Valerie; Sigurdsson, Asgeir; Trope, Martin
- Abstract
Ritter ALS, Ritter AV, Murrah V, Sigurdsson A, Trope M. Pulp revascularization of replanted immature dog teeth after treatment with minocycline and doxycycline assessed by laser Doppler flowmetry, radiography, and histology. Dent Traumatol 2004; 20: 75–84. © Blackwell Munksgaard, 2004. This study investigated the effect of topical antibiotic treatment on pulp revascularization in replanted teeth. Thirty-four immature teeth were selected from three young dogs. Baseline radiographs and laser Doppler flowmetry (LDF) readings were obtained. Specimens were randomly divided into four groups: Thirty-eight teeth were extracted, kept dry for 5 min, and either (Group 1) covered with minocycline mixture (G1, n = 11), (Group 2) soaked in doxycycline (G2, n = 11), or (Group 3) soaked in saline (G3-negative control, n = 6), and replanted. Teeth in Group 4 were not extracted (positive control, n = 6). Postoperative radiographs and LDF readings were obtained for 2 months after replantation. After sacrifice, the jaws were collected and processed for light microscopy. Pre- and postreplantation LDF readings and radiographs, and histologic findings were analyzed to assess revascularization. Pulp revascularization occurred in 91% (G1), 73% (G2), and 33% (G3) of the specimens. In conclusion, minocycline facilitates pulp revascularization in replanted immature teeth after replantation.
- Subjects
DENTAL extraction; DOGS; SIDE effects of antibiotics; DENTAL therapeutics; DENTISTRY; ORAL medicine
- Publication
Dental Traumatology, 2004, Vol 20, Issue 2, p75
- ISSN
1600-4469
- Publication type
Article
- DOI
10.1111/j.1600-4469.2004.00225.x