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- Title
Comparison of the Accuracy of Blastocystis hominis Diagnosis Methods Using Direct Examination and Jones Medium Culture: A Systematic Review and Meta-analysis.
- Authors
Athif Matondang, Muhammad Hafizh; Darlan, Dewi Masyitah; Lubis, Rodiah Rahmawaty; Andriyani, Yunilda
- Abstract
Introduction: Blastocystis hominis is a unicellular Stramenopile that inhabits the large intestine in humans and other hosts. Blastocystis hominis is very common in human samples in developing countries. Meta-analysis of Blastocystis hominis diagnosis method is very limited. Teh study aims to compare the accuracy between direct examination method and Jones’ medium culture for the diagnosis of Blastocystis hominis. Methods: A meta-analysis research conducted by collecting articles from PubMed, Science Direct, Cochrane Library, ProQuest, EBSCO, DOAJ and Wiley Library from 2011-2021 that match the inclusion and exclusion criteria. Articles will be assessed using the Newcastle Ottawa Scale and analyzed using Review Manager 5.4. Results: Of the 1700 articles searched, 4 articles were used for the systematic review and meta-analysis. The results of the Jones medium culture diagnostic test (100% sensitivity and 92% specificity) were higher than direct examination (43.5% sensitivity and 100% specificity). Discussion: Jones’ medium culture shows a better sensitivity compared to direct examination method. This happens because the culture process increases the number of Blastocystis hominis in feces samples so that positive findings under microscope examination is more likely to occur. Conclusion: Jones medium culture is a better diagnostic method for examination of Blastocystis hominis than direct examination.
- Subjects
BLASTOCYSTIS; DIAGNOSIS methods; LARGE intestine; DIAGNOSTIC examinations; DEVELOPING countries
- Publication
Malaysian Journal of Medicine & Health Sciences, 2024, Vol 20, p57
- ISSN
1675-8544
- Publication type
Article