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- Title
Mapping rainbow trout immune genes involved in inflammation reveals conserved blocks of immune genes in teleosts.
- Authors
Phillips, R. B.; Ventura, A. B.; DeKoning, J. J.; Nichols, K. M.
- Abstract
We report the genetic map location of 14 genes involved in the inflammatory response to salmonid bacterial and viral pathogens, which brings the total number of immune genes mapped in rainbow trout ( RT, Oncorhynchus mykiss) to 61. These genes were mapped as candidate genes that may be involved in resistance to bacterial kidney disease, as well as candidates for known QTL for resistance to infectious hematopoietic necrosis virus, infectious pancreatic necrosis virus and Ceratomyxa shasta. These QTL map to one or more of the linkage groups containing immune genes. The combined analysis of these linkage results and those of previously mapped immune genes in RT shows that many immune genes are found in syntenic blocks of genes that have been retained in teleosts despite species divergence and genome duplication events.
- Subjects
FISH genetics; ANIMAL genome mapping; OSTEICHTHYES; RAINBOW trout; CERATOMYXA shasta; BACTERIAL kidney disease (Fish disease); INFECTIOUS hematopoietic necrosis virus; INFECTIOUS pancreatic necrosis virus
- Publication
Animal Genetics, 2013, Vol 44, Issue 1, p107
- ISSN
0268-9146
- Publication type
Article
- DOI
10.1111/j.1365-2052.2011.02314.x