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- Title
Genetic variation in the ovine uncoupling protein 1 gene: association with carcass traits in New Zealand ( NZ) Romney sheep, but no association with growth traits in either NZ Romney or NZ Suffolk sheep.
- Authors
Yang, G.; Forrest, R.; Zhou, H.; Hodge, S.; Hickford, J.
- Abstract
The uncoupling protein 1 ( UCP1) plays an important role in the regulation of lipolysis and thermogenesis in adipose tissues. Genetic variation within three regions (the promoter, intron 2 and exon 5) of the ovine UCP1 gene ( UCP1) was investigated using polymerase chain reaction-single-strand conformational polymorphism ( PCR- SSCP) analyses. These revealed three promoter variants (designated A, B and C) and two intron 2 variants ( a and b). The association of this genetic variation with variation in lamb carcass traits and postweaning growth was investigated in New Zealand ( NZ) Romney and Suffolk sheep. The presence of B in a lamb's genotype was associated with decreased subcutaneous carcass fat depth (V- GR) (p = 0.004) and proportion of total lean meat yield of loin meat (p = 0.005), and an increased proportion of total lean meat yield of hind-leg meat (p = 0.018). In contrast, having two copies of C was associated with increased V- GR (p < 0.001) and proportion of total lean meat yield of shoulder meat (p = 0.009), and a decreased hind-leg yield (p = 0.032). No associations were found with postweaning growth. These results suggest that ovine UCP1 is a potential gene marker for carcass traits.
- Subjects
UNCOUPLING protein genetics; ROMNEY Marsh sheep; SHEEP genetics; LIPOLYSIS; BODY temperature regulation
- Publication
Journal of Animal Breeding & Genetics, 2014, Vol 131, Issue 6, p437
- ISSN
0931-2668
- Publication type
Article
- DOI
10.1111/jbg.12097