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- Title
Triple combination treatment with fractional CO<sub>2</sub> laser plus topical betamethasone solution and narrowband ultraviolet B for refractory vitiligo: a prospective, randomized half-body, comparative study.
- Authors
Li, Lu; Wu, Yan; Li, Li; Sun, Yan; Qiu, Li; Gao, Xing‐Hua; Chen, Hong‐Duo
- Abstract
Vitiligo on extremities and/or bony prominences is very resistant to treatment. Twenty-five patients with symmetrical and stable vitiligo on extremities and/or bony prominences were enrolled. The treatment side received fractional carbon dioxide laser followed by topical compound betamethasone solution and narrowband ultraviolet B phototherapy. The control side received laser treatment plus phototherapy. The result of treatment side showed that 44% patients achieved over 50% re-pigmentation and patient satisfaction score was 5.12 ± 3.23, higher than those of control ( p < 0.05). Adverse events were slight and tolerable. The triple combination treatment could be used as an alternative modality for refractory vitiligo.
- Subjects
HYPOPIGMENTATION; VITILIGO; PIGMENTATION disorders; COMBINATION drug therapy; PHOTOTHERAPY; RANDOMIZED controlled trials; THERAPEUTICS
- Publication
Dermatologic Therapy, 2015, Vol 28, Issue 3, p131
- ISSN
1396-0296
- Publication type
Article
- DOI
10.1111/dth.12202