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- Title
Steroid acne vs. Pityrosporumfolliculitis: the incidence ofPityrosporum ovaleand the effect of antifungal drugs in steroid acne.
- Authors
Yu, Hee-Joon; Lee, Soo-Keun; Son, Sook Ja; Kim, Yun Suck; Yang, Hong Yoon; Kim, Jae Hong
- Abstract
Background Steroid acne is a folliculitis that can result from systemic or topical administration of steroid, and has been described as showing a similar clinical picture to Pityrosporum folliculitis, but there have been few reports about the incidence of Pityrosporum ovale and the effect of antimycotic drugs in steroid acne and other acneiform eruptions. Our purpose was to describe the association between steroid acne and P. ovale, and to confirm the superior efficacy of oral antifungal drugs over anti-acne drugs in the treatment of steroid acne. Methods The history, clinical features direct microscopy, histopathologic analysis, and therapeutic results of 125 cases with steroid acne or other acneiform eruptions were described and compared. Results Over 80% of patients with acneiform eruption receiving systemic steroid revealed significant numbers of P. ovale in the lesional follicle. Furthermore, oral antifungal drug (itraconazole) showed significantly better clinical and mycologic effects than any other group of medications used in this study. Conclusions Steroid acne and other acneiform eruptions showing discrete follicular papules and/or pustules localized to the upper trunk and acneiform facial skin lesions associated with multiple acneiform lesions on the body in the summer period should be suspected as Pityrosporum folliculitis. In addition, oral antifungal drugs recommended for Pityrosporum folliculitis; however, it will require a larger case-control study to confirm the superiority of antifungal therapy over anti-acne treatment.
- Subjects
ANTIFUNGAL agents; MALASSEZIA ovale; ACNE; SKIN disease treatment; DRUG efficacy
- Publication
International Journal of Dermatology, 1998, Vol 37, Issue 10
- ISSN
0011-9059
- Publication type
Article
- DOI
10.1046/j.1365-4362.1998.00229.x