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- Title
Unprecedented Multicomponent Reaction of Indoles, CS<sub>2</sub> and Nitroarenes: Stereoselective Synthesis of (Z)‐3‐((Arylamino)methylene)indoline‐2‐thiones.
- Authors
Qin, Qi; Liu, Xin‐Lian; Ma, Ai‐Jun; Zhang, Xiang‐Zhi; Peng, Jin‐Bao
- Abstract
An efficient method for the stereoselective synthesis of (Z)‐3‐((arylamino)methylene)indoline‐2‐thiones have been developed via a novel multicomponent reaction of indoles, CS2 and nitroarenes. A range of functionalized indoline‐2‐thiones were prepared in moderate to good yields from easily available starting materials. The indoline‐2‐thione products can be easily derivatized to give biologically active thieno[2,3‐b]indole and thiopyrano[2,3‐b]indole skeletons in high yields.
- Subjects
NITROAROMATIC compounds; INDOLE compounds; SKELETON; INDOLE
- Publication
Chemistry - An Asian Journal, 2021, Vol 16, Issue 23, p3890
- ISSN
1861-4728
- Publication type
Article
- DOI
10.1002/asia.202101008