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- Title
A presença de patógenos periodontais e sua relação com o gene MBL2 em pacientes portadores de periodontite crônica.
- Authors
Cimões, Renata; Roberto Eleutério de Souza, Paulo; de Carvalho Farias Vajgel, Bruna; Aguiar de Melo Dia, Rayanne Soraia; Ferreira, Betânia
- Abstract
Objective: Considering the role of MBL2 in innate immunity and its importance for periodontitis -- infectious multifactorial disease --, this study aimed to evaluate the association of the MBL2 gene polymorphism with the presence of periodontal pathogens in patients with chronic periodontitis. Methods: The convenience sample consisted of 29 patients diagnosed with chronic periodontitis who sought dental treatment from August 2008 to July 2009. Samples were collected from subgingival plaque of the four sites with deepest probing depth and the presence of periodontal pathogens was analyzed by PCR. Desquamated cells from oral mucosa were also collected to evaluate the MBL2 polymorphism by Q-PCR technique. Results: Regarding the MBL2, 19 (65.5%) patients presented the genotype A/A, 10 (34.5%) had genotype A/O, and none had genotype O/O. It was not observed significant association between the presence of periodontal pathogens and found genotypes (p > 0.05). Conclusion: Our results suggest that there is no association between genotypes and the presence of periodontal pathogens in patients with chronic periodontitis.
- Publication
Journal of Clinical Dentistry & Research, 2018, Vol 15, Issue 2, p170
- ISSN
2447-911X
- Publication type
Article
- DOI
10.14436/2447-911x.15.2.170-179.oar