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- Title
Temporal Lobe Epilepsy after Refractory Status Epilepticus: An Illustrative Case and Review of the Literature.
- Authors
Boyd, J. Gordon; Debicki, Derek B.; Young, G. Bryan
- Abstract
New onset refractory status epilepticus (NORSE) is a relatively newly defined disease entity, where otherwise healthy individuals develop unrelenting seizures that do not respond to conventional anticonvulsant therapy and may require months of therapy with anesthetic drugs. We have described a case of NORSE who subsequently developed mesial temporal lobe sclerosis (MTS) and recurrent temporal lobe seizures. We discuss the possible pathophysiological mechanisms by which refractory seizures may contribute to the development of temporal lobe epilepsy (TLE).
- Subjects
STATUS epilepticus; TEMPORAL lobe epilepsy; SYSTEMATIC reviews; ANTICONVULSANTS; ANESTHETICS; PATHOLOGICAL physiology; NEUROSCIENCES
- Publication
Epilepsy Research & Treatment, 2012, p1
- ISSN
2090-1348
- Publication type
Article
- DOI
10.1155/2012/209701