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- Title
A Case of Rapidly Progressive, Fatal Mycosis Fungoides Presenting as a Haematoma-like Lesion.
- Authors
Tomoyasu HATTORI; Akihiko UCHIYAMA; Osamu TAGO; Yayoi NAGAI; Osamu ISHIKAWA
- Abstract
Mycosis fungoides usually follows an indolent clinical course. We report here a rapidly progressive case of mycosis fungoides with peculiar clinical and histological features, presenting as a haematoma-like mass on the thigh accompanied by multiple reddish brown erythematous lesions on the trunk and extremities. Histopathologically, the erythematous lesions showed epidermotropism of atypical T lymphocytes expressing CD4 and prominent syringotropism without syringometaplasia. The haematoma-like lesion consisted of diffuse and dense infiltrates of medium-to-large-sized pleomorphic lymphocytic cells expressing CD30, suggesting that CD30+ large-cell transformation had occurred. Mycosis fungoides presenting as a haematoma-like lesion is rare and may be a poor prognostic sign.
- Subjects
MYCOSIS fungoides; LYMPHOPROLIFERATIVE disorders; HISTOLOGY; T cells; CELL proliferation
- Publication
Acta Dermato-Venereologica, 2013, Vol 93, Issue 6, p707
- ISSN
0001-5555
- Publication type
Article
- DOI
10.2340/00015555-1586