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- Title
Glycine Metabolism and Glycine Synthase Activity during the Postnatal Development of Rat Brain.
- Authors
Lahoya, J.L.; Benavides, J.; Ugarte, M.
- Abstract
Glycine synthase from rat brain mitochondria shows an apparent Km for glycine of 2.6 mM. Glycine synthase from rat brain homogenate has a maximum of activity at the 10th day of life. However, each area of the central nervous system shows a different developmental pattern of glycine synthase activity. Both the 14COa production from (U-14C)-glycine and the incorporation of the radioactivity from the (U-14C)-glycine to the acid-insoluble fraction by cortex slices has a developmental profile similar to the glycine synthase activity in this area, having a maximum on the 10th day. Copyright © 1980 S. Karger AG, Basel
- Publication
Developmental Neuroscience, 1980, Vol 3, Issue 2, p75
- ISSN
0378-5866
- Publication type
Article
- DOI
10.1159/000112379