We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Effectiveness of autologous fibrin glue in preventing post-thoracotomy air leaks: a randomized controlled trial.
- Authors
Zabihi, Fariba; Mehri, Ali; Ahmadi, Ghazale; Alamdari, Daryoush Hamidi; Kabiri, Mona; Amirianfar, Azam; Rezaei, Reza
- Abstract
Introduction: Post-thoracotomy air leaks remain a significant challenge in thoracic surgery. Aim: This randomized controlled trial assessed the efficacy of autologous fibrin glue in reducing air leaks following thoracotomy procedures. Material and methods: Conducted as a single-center, single-blind, randomized clinical trial, the study enrolled adult patients undergoing lung resection or decortication at a thoracic surgery clinic. Participants were randomly assigned to either the intervention group, receiving autologous fibrin glue application during surgery, or the control group, undergoing standard surgical procedures without glue application. Key inclusion criteria were adult patients undergoing elective thoracotomy for lung resection or decortication, while exclusion criteria included patients with severe comorbidities or contraindications to fibrin glue. Results: A total of 40 patients were enrolled and randomized equally to the two groups. The group treated with autologous fibrin glue demonstrated a significant reduction in the duration of air leakage and chest tube drainage, along with a shorter hospital stay, compared to the control group. There were no statistically significant differences in postoperative complications between the groups. Conclusions: The application of autologous fibrin glue during thoracotomy procedures significantly reduces postoperative air leaks and hospitalization duration without increasing complication rates. This finding suggests a beneficial role of fibrin glue in thoracic procedures requiring lung resection or decortication.
- Subjects
FIBRIN tissue adhesive; THORACOTOMY; RANDOMIZED controlled trials; INSUFFLATION; THORACIC surgery; CHEST tubes; SURGICAL complications
- Publication
Polish Journal of Thoracic & Cardiovascular Surgery / Kardiochirurgia i Torakochirurgia Polska, 2024, Vol 21, Issue 1, p15
- ISSN
1731-5530
- Publication type
Article
- DOI
10.5114/kitp.2024.138579