We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Reacción de antígenos de Leishmania (Leishmania) mexicana con sueros de pacientes con leishmaniosis cutánea de Sinaloa, México.
- Authors
Salazar-Mejía, Patricia Guadalupe; Tejeda-Aguirre, Celia Rosa; López-Moreno, Héctor Samuel
- Abstract
Objective. To detect Leishmania mexicana antigens reacting with sera of patients with cutaneous leishmaniasis (CL). Material and methods. A crude extract of L. mexicana was used as antigen for 2-D Western blot using sera from 5 patients with CL and controls from Sinaloa, Mexico during 2008. Results. Five antigens were detected in the five infected patients analyzed; their molecular weights and isoelectric points were: 26 kDa (pI 7.8), 27 kDa (pI 8.1), 28 kDa (pI 8.6), 29 kDa (pI 8.5) and 31 kDa (pI 9.0). Conclusion. New potentially immunodominant L. mexicana antigens were detected, suggesting that this parasite could be the species responsible for human infection in Sinaloa.
- Subjects
MEXICO; LEISHMANIASIS diagnosis; ANTIGEN analysis; CUTANEOUS leishmaniasis; IMMUNOGLOBULINS; IMMUNITY; DIAGNOSIS
- Publication
Salud Pública de México, 2010, Vol 52, Issue 2, p165
- ISSN
0036-3634
- Publication type
Article
- DOI
10.1590/S0036-36342010000200009