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- Title
Colchicine in coronary artery disease.
- Authors
Katira, Arnav; Katira, Ravish
- Abstract
Coronary artery disease (CAD) is a major cause of morbidity and mortality worldwide. Inflammation has been seen to be a key feature of atherosclerosis and CAD, with a raised C-reactive protein being a marker of poor prognosis. Thus, the role of anti-inflammatory agents has been investigated in CAD. Colchicine is a well-known, inexpensive drug with marked anti-inflammatory effects. Here, we discuss the role of colchicine in stable CAD and post-acute coronary syndrome. We suggest that colchicine may play a key role in prevention of cardiovascular events in patients with stable and unstable CAD as colchicine is associated with a reduction in the rate of myocardial infarction and other major cardiovascular outcomes.
- Subjects
MYOCARDIAL infarction complications; ACUTE coronary syndrome; ATHEROSCLEROSIS; CORONARY artery disease; COLCHICINE; DISEASE complications
- Publication
Postgraduate Medical Journal, 2022, Vol 98, Issue 1163, p718
- ISSN
0032-5473
- Publication type
journal article
- DOI
10.1136/postgradmedj-2020-139611