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- Title
Performance evaluation the new automated Atellica Hema 580 hematology analyzer.
- Authors
Schapkaitz, E.; Baiden, A.; Raburabu, S.
- Abstract
Introduction: The Atellica Hema (Siemens Healthineers, Tarrytown, NY, USA) is a new generation multi‐parameter analyzer for full blood count, 6‐part differential and reticulocyte testing by impedance variation and fluorescence flow cytometry. In this study, we verified the whole blood and limited body fluid modes of the Atellica Hema 580. Methods: We evaluated precision, linearity, carry‐over, throughput and performed a method comparison to assess the performance of the Atellica Hema 580. For comparison of the Atellica Hema 580 with the Sysmex XN‐1000 (Sysmex, Kobe, Japan), 140 samples from adult and pediatric patients including both normal and abnormal hematology profiles were analyzed in parallel. Results: The Atellica Hema 580 demonstrated acceptable imprecision within the manufacturer's specifications for whole blood and body fluid modes, good linearity for high and low ranges and no significant carryover. The full blood count, differential and reticulocyte correlated well with the Sysmex XN‐1000, except for mean cell hemoglobin concentration, basophil and large immature cells. The optical platelet count, reflexed in 34 samples with a platelet count <150 × 109/l, showed a strong correlation with the fluorescent platelet count on the Sysmex XN‐1000. The morphology flagging efficiency was 92% for white blood cells, 95% for red blood cells and 87% for platelets. Conclusion: The Atellica Hema 580 showed good analytical performance and workflow efficiency for a wide range of patient samples.
- Subjects
JAPAN; BODY fluid analysis; FLOW cytometry; BASOPHILS; RETICULOCYTES; HEMATOLOGY; AUTOANALYZERS; BLOOD platelets; LEUCOCYTES; WORKFLOW; LEUKOCYTE count; BIOELECTRIC impedance; BLOOD cell count; ERYTHROCYTES
- Publication
International Journal of Laboratory Hematology, 2024, Vol 46, Issue 1, p63
- ISSN
1751-5521
- Publication type
Article
- DOI
10.1111/ijlh.14170