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- Title
Undifferentiated (embryonal) sarcoma of the liver: report of 31 cases.
- Authors
Stocker, J. Thomas; Ishak, Kamal G.; Stocker, J T; Ishak, K G
- Abstract
Thirty-one cases of undifferentiated (embryonal) sarcoma of the liver are presented. The tumor is found predominantly in the pediatric age group, the majority of patients (51.6%) being between 6 and 10 years of age. An abdominal mass and pain are the usual presenting symptoms. Radiographic examination is nonspecific except to demonstrate a space-occupying lesion of the liver. The tumors are large, single, usually globular and well demarcated, and have multiple cystic areas of hemorrhage, necrosis, and gelatinous degeneration. Histologic examination shows a pseudocapsule partially separating the normal liver from undifferentiated sarcomatous cells that, near the periphery of the tumor, surround entrapped hyperplastic or degenerating bile duct-like structures. Eosinophilic globules that are PAS positive are usually found within and adjacent to tumor cells. Areas of necrosis and hemorrhage are prominent. The prognosis is poor, with a median survival of less than 1 year following diagnosis.
- Publication
Cancer (0008543X), 1978, Vol 42, Issue 1, p336
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(197807)42:1<336::AID-CNCR2820420151>3.0.CO;2-V