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- Title
Value of 111Indium chloride bone marrow scanning in the differential diagnosis of blood count depression in lymphoma.
- Authors
Gilbert, Edward H.; Glatstein, Eli; Goris, Michael L.; Earle, John D.; Gilbert, E H; Glatstein, E; Goris, M L; Earle, J D
- Abstract
In patients with Hodgkin's disease or non-Hodgkin's lymphoma, the etiology of low peripheral blood counts is often difficult to determine. Often it is based on the results of a "random" bone marrow biopsy and/or aspirate, plus evaluation of circulating peripheral blood elements. However, these tests may be misleading. The present study evaluates the usefulness of 111Indium chloride bone marrow scanning in conjunction with marrow biopsies in distinguishing intrinsic from extrinsic causes for low peripheral blood counts. Thirty consecutive patients with Hodgkin's disease or non-Hodgkin's lymphoma, presenting with low peripheral blood counts and without any form of antineoplastic treatment for at least 5 weeks, were analyzed. Scan ratings were felt to be clinically accurate in 27 of the 30 patients analyzed (90%). In 18 patients (60%), the scan provided information which was not provided by any other standard test. 111Indium chloride scanning in conjunction with a marrow biopsy appears to be a useful, accurate means of evaluating bone marrow function in patients with depressed peripheral blood counts.
- Publication
Cancer (0008543X), 1978, Vol 41, Issue 1, p143
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(197801)41:1<143::AID-CNCR2820410123>3.0.CO;2-H