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- Title
Function Blocking Autoantibodies Against Matrix Metalloproteinase-1 in Patients with Systemic Sclerosis.
- Authors
Sato, Shinichi; Hayakawa, Ikuko; Hasegawa, Minoru; Fujimoto, Manabu; Takehara, Kazuhiko
- Abstract
Studies the hypothesis that systemic autoimmunity in systemic sclerosis (SSc) induced anti-matrix metalloproteinase-1 (MMP) autoantibodies that inhibited matrix metallo-proteinase-1 activity, resulting in collagen accumulation. Characteristics of SSc; Observation related to enzyme-linked immunosorbent assay using human recombinant matrix metalloproteinase-1; Frequency of anti-MMP-1 antibody in collagen diseases.
- Subjects
SYSTEMIC scleroderma; METALLOPROTEINASES
- Publication
Journal of Investigative Dermatology, 2003, Vol 120, Issue 4, p542
- ISSN
0022-202X
- Publication type
Article
- DOI
10.1046/j.1523-1747.2003.12097.x