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- Title
Transoral laser microsurgery for early glottic cancer as one-stage single-modality therapy.
- Authors
Lee, Hyoung Shin; Chun, Bong‐Gwon; Kim, Sung Won; Kim, Seung Tae; Oh, Jung Ho; Hong, Jong Chul; Lee, Kang Dae
- Abstract
Objectives/Hypothesis A study was undertaken to determine the oncologic outcomes in a consecutive series of early glottic carcinomas treated with transoral CO2 laser microsurgery (TLM) as a one-stage single-modality therapy, without any postoperative radiation therapy or retreatment with laser. We further evaluated correlations between the oncologic outcomes and clinicopathologic factors including tumor location and surgical margin. Study Design Retrospective analysis of medical records. Methods The medical records of 118 consecutive patients with early stage (T1, T2) glottic carcinoma who underwent TLM by a single surgeon as an initial treatment from 1997 to 2011 were retrospectively reviewed. The oncologic outcomes were evaluated, and correlations to clinicopathologic factors were analyzed. Results The 5-year disease-free survival, ultimate local control with laser alone, disease-specific survival, overall survival, and organ preservation rates were 87.9%, 94.2%, 99.0%, 92.2%, and 96.2%, respectively. Neither the reported surgical margin nor the extension of tumor to the anterior commissure, arytenoid, subglottis, and ventricle showed any significant impact on local control or survival. Conclusions Transoral CO2 laser microsurgery as one-stage single-modality therapy resulted in a high rate of local control and a high survival rate in selected cases of early glottic carcinoma, regardless of the location of tumor and histopathology report on the surgical margin. Level of Evidence 4 Laryngoscope, 123:2670-2674, 2013
- Subjects
MICROSURGERY; GLOTTIS cancer; LASER surgery; HEALTH outcome assessment; ONCOLOGIC surgery; CARBON dioxide lasers; POSTOPERATIVE care; CANCER radiotherapy
- Publication
Laryngoscope, 2013, Vol 123, Issue 11, p2670
- ISSN
0023-852X
- Publication type
Article
- DOI
10.1002/lary.24080