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- Title
Identification and Characterization of an Inhibitor of Trichothecene 3-0-Acetyltransferase, TRI101, by the Chemical Array Approach.
- Authors
Yuichi NAKAJIMA; Tatsuro KAWAMURA; Kazuyuki MAEDA; Hinayo ICHIKAWA; Takayuki MOTOYAMA; Yasumitsu KONDOH; Tamio SAITO; Tetsuo KOBAYASHI; Minora YOSHIDA; Hiroyuki OSADA; Makoto KIMURA
- Abstract
The article focuses on a research regarding trichothecene acetyltransferase inhibitor's identification and characterization by chemical array approach. It notes that the sesquiterpenoid mycotoxic nature of trichothecenes which terminate protein synthesis in eukaryotes like Fusarium graminearum which infects and contaminates cereal grains. It further mentions the determination of biosynthetic pathways which demonstrate the involvement of genes in trichothecene synthesis and regulation.
- Subjects
TRICHOTHECENES; ACETYLTRANSFERASES; SESQUITERPENES; MYCOTOXICOSES; GENETIC regulation; PROTEIN synthesis
- Publication
Bioscience, Biotechnology & Biochemistry, 2013, Vol 77, Issue 9, p1958
- ISSN
0916-8451
- Publication type
Article
- DOI
10.1271/bbb.130153