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- Title
Red Cell Distribution Width and Futile Recanalization in Individuals with Acute Ischemic Stroke following Endovascular Treatment.
- Authors
Zhengyang Wang; Yin Liu
- Abstract
Background: Previous studies reported that red cell distribution width (RDW) was related to acute ischemic stroke (AIS). Endovascular treatment (EVT) still faces a huge challenge: futile recanalization. The goal of our study was to investigate the relationship between futile recanalization and RDW in AIS patients receiving EVT. Methods: We retrospectively identified 188 AIS individuals with anterior circulation occlusion throughout EVT and obtained complete or near-total recanalization. The subjects were classified into futile recanalization group by their 3-month modified Rankin scale (mRS) score ≥3. The predictive value of RDW was calculated using receiver operating characteristic (ROC) curves, area under the curve (AUC) values, and logistic regression approaches. Results: One hundred and eleven (59.0%) patients were defined as futile recanalization. The RDW was observed as an novel factor of futile recanalization in the multivariate regression model ([OR, odd-ratio] = 5.233, 95% [CI, confidence interval] = 2.656–10.307; p < 0.001). According to the ROC, the model integrating RDW with other risk factors had a relatively higher AUC compared than the RDW alone model (0.944 vs 0.798; p < 0.001) via DeLong’s test. Conclusions: Higher RDW is associated with poor functional outcome in anterior circulation AIS patients undergoing EVT at 3 months.
- Subjects
ISCHEMIC stroke; ERYTHROCYTES; ENDOVASCULAR surgery; LOGISTIC regression analysis; BLOOD circulation
- Publication
Journal of Integrative Neuroscience, 2023, Vol 22, Issue 3, p1
- ISSN
0219-6352
- Publication type
Article
- DOI
10.31083/j.jin2203078