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- Title
Errors and Nonadherence in Pediatric Oral Chemotherapy Use.
- Authors
Walsh, Kathleen; Ryan, Jamie; Daraiseh, Nancy; Pai, ahna
- Abstract
Background: Nonadherence and medication error both limit the effectiveness of oral chemotherapy. The overlap between nonadherence and medication error is not well studied in children, and interventions strategies differ for each. Our objective was to describe nonadherence and errors in children with cancer to inform future interventions. Methods: Nonadherence was measured using two self-report tools. Medication error was measured using medication review and observation of administration at home. Two clinicians made judgments about whether each error also represented an episode of nonadherence. Results: Of 72 errors detected in 92 home visits, 27 were also instances of nonadherence. For example, parents gave a child 1 tablet of mer-captopurine every day rather than the prescribed 1 tablet 5 days a week and Vi tablet on weekends. Clinician reviewers judged that family interventions and health system interventions would be most effective in preventing the errors and nonadherence identified in this population of children with cancer. Discussion: The relationship between medication errors and nonadherence is not well described in the literature. Our data indicate that medication error and non-adherence coexist in the same population and in the same patient. Interventions should address both to most effectively support self-management.
- Subjects
GEORGIA; MASSACHUSETTS; ANTINEOPLASTIC agents; DRUGS; HOME care services; RESEARCH methodology; MEDICATION errors; SCIENTIFIC observation; ORAL drug administration; PARENTS; PATIENT compliance; SELF-evaluation; TUMORS in children
- Publication
Oncology, 2016, Vol 91, Issue 4, p231
- ISSN
0030-2414
- Publication type
Article
- DOI
10.1159/000447700