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- Title
B-006 LIVING-DONOR LOBAR LUNG TRANSPLANTATION PROVIDES SIMILAR SURVIVAL TO CADAVERIC LUNG TRANSPLANTATION EVEN FOR SICKER PATIENTS.
- Authors
Date, Hiroshi; Aoyama, A.; Sato, M.; Yamada, T.; Hijiya, K.; Kondo, T.; Motoyama, H.; Takahashi, M.; Ohata, K.; Chen, F.
- Abstract
Objectives: Living-donor lobar lung transplantation (LDLLT) has been performed as a life-saving procedure for critically ill patients who are unlikely to survive the long wait for cadaveric lungs. The purpose of this study was to compare preoperative conditions and outcomes of LDLLT with those of conventional cadaveric lung transplantation (CLT).Methods: A new lung transplant programme was established in 2008 in our institution. Between June 2008 and January 2014, we performed 77 lung transplants including 42 LDLLTs (10 single and 32 bilateral), and 35 CLTs (21 single and 14 bilateral). The average waiting time for cadaveric donor was 761 days. All data were analyzed retrospectively as of January 2014.Results: LDLLT included 12 children (29%) and CLT included no children; however, the average age was similar (36.9 years vs 38.6 years, P = 0.56). Regarding the distribution of preoperative diagnoses, pulmonary fibrosis was more common in LDLLT than in CLT (42.9% vs 20.0%, P =0.03). LDLLT included less walkable patients than CLT (42.9% vs 85.7%, P = 0.0001) and tended to include more ventilator-dependent patients (11.9% vs 2.9%, P = 0.14). Duration of postoperative mechanical ventilation required was longer in LDLLT than in CLT (15.6 days vs 8.4 days, P = 0.03). However, 1- and 3-year survival rates were similar between the two groups (92.6% and 88.9% vs 88.0% and 82.5%, P = 0.356). All living-donors have returned to their previous life styles without restriction.Conclusions: Although preoperative recipient's condition was worse, LDLLT provided similar survival to CLT. LDLLT is a viable option for sick patients who would not survive a long waiting time for cadaveric donors.Disclosure: No significant relationships.
- Publication
Interactive Cardiovascular & Thoracic Surgery, 2014, Vol 18, Issue suppl_1, pS2
- ISSN
1569-9293
- Publication type
Article
- DOI
10.1093/icvts/ivu167.6