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- Title
Symptom patterns and life with post-acute COVID-19 in children aged 8-17 years: a mixed-methods study protocol.
- Authors
Faux-Nightingale, Alice; Burton, Claire; Twohig, Helen; Blagojevic-Bucknall, Milica; Carroll, Will; Chew-Graham, Carolyn A.; Dunn, Kate; Gilchrist, Francis; Helliwell, Toby; Lawton, Oliver; Lawton, Sarah; Mallen, Christian; Saunders, Benjamin; van der Windt, Danielle; Welsh, Victoria
- Abstract
Background: While there is a substantial body of knowledge about acute COVID-19, less is known about long-COVID, where symptoms continue beyond 4 weeks. Aim: To describe longer-term effects of COVID-19 infection in children and young people (CYP) and identify their needs in relation to long-COVID. Design & setting: This study comprises an observational prospective cohort study and a linked qualitative study, identifying participants aged 8-17 years in the West Midlands of England. Method: CYP will be invited to complete online questionnaires to monitor incidences and symptoms of COVID-19 over a 12-month period. CYP who have experienced long-term effects of COVID will be invited to interview, and those currently experiencing symptoms will be asked to document their experiences in a diary. Professionals who work with CYP will be invited to explore the impact of long-COVID on the wider experiences of CYP, in a focus group. Descriptive statistics will be used to describe the incidence and rates of resolution of symptoms, and comparisons will be made between exposed and non-exposed groups. Logistic regression models will be used to estimate associations between candidate predictors and the development of long-COVID, and linear regression will be used to estimate associations between candidate predictors. Qualitative data will be analysed thematically using the constant comparison method. Conclusion: This study will describe features and symptoms of long-COVID and explore the impact of long-COVID within the lives of CYP and their families, to provide better understanding of long-COVID and inform clinical practice.
- Subjects
ENGLAND; COVID-19; PATIENT participation; POST-acute COVID-19 syndrome; QUALITY of life; VACCINATION status; MEDICAL needs assessment; CHILDREN; ADOLESCENCE
- Publication
BJGP Open, 2023, Vol 7, Issue 2, p1
- ISSN
2398-3795
- Publication type
Article
- DOI
10.3399/BJGPO.2022.0149