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- Title
Mimosine detection in an outbreak of Leucaena leucocephala poisoning in horses.
- Authors
Machado, Mizael; Queiroz, Cintia; Gardner, Dale R.; Riet-Correa, Franklin
- Abstract
In Brazil, Leucaena leucocephala (Leg. Mimosoideae) poisoning has been described in sheep, goats, and horses. The leaves of this leguminous plant are highly palatable and contain the toxic non-protein amino acid mimosine. Mimosine concentrations associated with Leucaena toxicosis are not readily available in the literature. The present study describes the epidemiological findings, clinical signs, and toxicologic analysis of an outbreak of L. leucocephala poisoning in horses in Araguari, Triângulo Mineiro, Minas Gerais, Brazil. The outbreak affected three of four adult horses of the farm. The animals consumed the leaves spontaneously during the drought period (July to September). The horses exhibited moderate to severe alopecia of the tail and mane. Leaves of the plant were randomly sampled (50 g), dried at ambient temperature, and sent for mimosine analysis. Quantitative analysis by a high-performance liquid chromatography method (HLPC-UV) measured a concentration of 5.5 mg/g of mimosine in the dry plant material. The horses recovered after being removed from the paddocks that contained the toxic plant material. L. leucocephala poisoning should be considered a differential diagnosis for horses presenting alopecia in the state of Minas Gerais, and the toxicologic analysis results can be used for comparisons in future studies.
- Subjects
MIMOSINE; BALDNESS in animals; HORSES
- Publication
Revista Academica Ciencia Animal, 2022, Vol 20, p22
- ISSN
2596-2868
- Publication type
Abstract