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- Title
Effects of Prolonged Storage of Whole Plasma or Isolated Plasma DNA on the Results of Circulating DNA Quantification Assays.
- Authors
Sozzi, Gabriella; Roz, Luca; Conte, Davide; Mariani, Luigi; Andriani, Francesca; Verderio, Paolo; Pastorino, Ugo
- Abstract
The article presents a study on the effects of prolonged storage of whole plasma or isolated plasma DNA on the results of circulating DNA quantification assays. The result indicate that prolonged storage of both isolated DNA and whole plasma samples leads to substantial DNA degradation as measured by real-time polymerase chain reaction, PCR-based assays.
- Subjects
DNA; DNA polymerases; PLASMA cells; POLYMERASE chain reaction; PREDICATE calculus
- Publication
JNCI: Journal of the National Cancer Institute, 2005, Vol 97, Issue 24, p1848
- ISSN
0027-8874
- Publication type
Article
- DOI
10.1093/jnci/dji432