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- Title
Weight Loss Therapy Improves Pancreatic Endocrine Function in Obese Older Adults.
- Authors
Villareal, Dennis T.; Banks, Marian R.; Patterson, Bruce W.; Polonsky, Kenneth S.; Klein, Samuel
- Abstract
The article focuses on the ability of weight loss therapy to improve the pancreatic endocrine function in obese older adults in the U.S. based on a study. The plasma glucose concentration at 2 hours of the oral glucose tolerance test (OGTT) had significantly reduced in the treatment group at 22 weeks. The overall disposition index (DI) that adjusts β-cell insulin response had increased significantly in the treatment group. There were no significant differences in insulin clearance and glucagon reduction in control and treatment groups.
- Subjects
UNITED States; WEIGHT loss endocrinology; ENDOCRINE glands; OVERWEIGHT persons; HEALTH of older people; BLOOD plasma; PANCREATIC beta cells; GLUCAGON
- Publication
Obesity (19307381), 2008, Vol 16, Issue 6, p1349
- ISSN
1930-7381
- Publication type
Article
- DOI
10.1038/oby.2008.226