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A tumor suppressor role for EZH2 in diffuse midline glioma pathogenesis.
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- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01336-5
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- Article
Pre-clinical models of diffuse intrinsic pontine glioma.
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- Frontiers in Oncology, 2015, p. 1, doi. 10.3389/fonc.2015.00172
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- Article
Diffuse Intrinsic Pontine Glioma.
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- Journal of Child Neurology, 2016, v. 31, n. 12, p. 1377, doi. 10.1177/0883073815601495
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- Article
Tumour immune landscape of paediatric high-grade gliomas.
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- 2021
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- Publication type:
- journal article
Platelet-derived growth factor beta is a potent inflammatory driver in paediatric high-grade glioma.
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- 2021
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- Publication type:
- journal article
Splicing is an alternate oncogenic pathway activation mechanism in glioma.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28253-4
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- Article
T2-weighted images are superior to other MR image types for the determination of diffuse intrinsic pontine glioma intratumoral heterogeneity.
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- Child's Nervous System, 2018, v. 34, n. 3, p. 449, doi. 10.1007/s00381-017-3659-8
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- Article
Pax3 expression enhances PDGF-B-induced brainstem gliomagenesis and characterizes a subset of brainstem glioma.
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- Acta Neuropathologica Communications, 2014, v. 2, n. 1, p. 1, doi. 10.1186/s40478-014-0134-6
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- Article
Prenatal overexpression of platelet‐derived growth factor receptor A results in central nervous system hypomyelination.
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- Brain & Behavior, 2021, v. 11, n. 10, p. 1, doi. 10.1002/brb3.2332
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- Article
A High-Throughput In Vitro Drug Screen in a Genetically Engineered Mouse Model of Diffuse Intrinsic Pontine Glioma Identifies BMS-754807 as a Promising Therapeutic Agent.
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- PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0118926
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- Article
PD-0332991, a CDK4/6 Inhibitor, Significantly Prolongs Survival in a Genetically Engineered Mouse Model of Brainstem Glioma.
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- PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077639
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- Publication type:
- Article
Perifosine and CCI 779 Co-Operate to Induce Cell Death and Decrease Proliferation in PTEN-Intact and PTENDeficient PDGF-Driven Murine Glioblastoma.
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- PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0014545
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- Article
Heterozygosity for Pten Promotes Tumorigenesis in a Mouse Model of Medulloblastoma.
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- PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010849
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- Article
Pediatric Neuro-Oncology: Time to Go Molecular.
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- Oncology (08909091), 2016, v. 30, n. 5, p. 424
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- Article
Delta-24-RGD combined with radiotherapy exerts a potent antitumor effect in diffuse intrinsic pontine glioma and pediatric high grade glioma models.
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- Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0714-6
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- Publication type:
- Article
ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis.
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- Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-08823-9
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- Publication type:
- Article
The Effect of Atm Loss on Radiosensitivity of a Primary Mouse Model of Pten -Deleted Brainstem Glioma.
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- Cancers, 2022, v. 14, n. 18, p. N.PAG, doi. 10.3390/cancers14184506
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- Article
Sonic Hedgehog Pathway Activation Is Induced by Acute Brain Injury and Regulated by Injury-Related Inflammation.
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- Journal of Neuroscience, 2009, v. 29, n. 33, p. 10299, doi. 10.1523/JNEUROSCI.2500-09.2009
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- Article
Sox2, a marker for stem-like tumor cells in skin squamous cell carcinoma and hedgehog subgroup medulloblastoma.
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- EMBO Journal, 2014, v. 33, n. 18, p. 1984, doi. 10.15252/embj.201489479
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- Publication type:
- Article
Therapeutic targeting of transcriptional elongation in diffuse intrinsic pontine glioma.
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- Neuro-Oncology, 2021, v. 23, n. 8, p. 1348, doi. 10.1093/neuonc/noab009
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- Publication type:
- Article
Pharmacologic inhibition of lysine-specific demethylase 1 as a therapeutic and immune-sensitization strategy in pediatric high-grade glioma.
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- Neuro-Oncology, 2020, v. 22, n. 9, p. 1302, doi. 10.1093/neuonc/noaa058
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- Publication type:
- Article
Epigenetic reprogramming and chromatin accessibility in pediatric diffuse intrinsic pontine gliomas: a neural developmental disease.
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- Neuro-Oncology, 2020, v. 22, n. 2, p. 195, doi. 10.1093/neuonc/noz218
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- Publication type:
- Article
HDAC inhibitors to the rescue in sonic hedgehog medulloblastoma.
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- Neuro-Oncology, 2019, v. 21, n. 9, p. 1091, doi. 10.1093/neuonc/noz115
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- Article
THER-31. TARGETING THE HISTONE DEMETHYLASE LSD1 FOR SELECTIVE APOPTOSIS AND IMMUNE-SENSITIZATION IN PEDIATRIC DIPG.
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- Neuro-Oncology, 2019, v. 21, p. ii120, doi. 10.1093/neuonc/noz036.236
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- Publication type:
- Article
TMOD-09. TUMOR ASSOCIATED MACROPHAGE DYNAMICS IN PEDIATRIC HIGH-GRADE GLIOMAS.
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- Neuro-Oncology, 2019, v. 21, p. ii123, doi. 10.1093/neuonc/noz036.247
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- Publication type:
- Article
DIPG-26. ACVR1 R206H COOPERATES WITH H3.1K27M IN PROMOTING DIFFUSE INTRINSIC PONTINE GLIOMA PATHOGENESIS.
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- Neuro-Oncology, 2019, v. 21, p. ii74, doi. 10.1093/neuonc/noz036.047
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- Publication type:
- Article
DIPG-30. ISOFORM SPECIFIC OVEREXPRESSION OF WILMS' TUMOR PROTEIN IN DIFFUSE INTRINSIC PONTINE GLIOMAS.
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- Neuro-Oncology, 2019, v. 21, p. ii75, doi. 10.1093/neuonc/noz036.051
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- Publication type:
- Article
DIPG-04. TRANSLATION OF DNX-2401 FROM THE BENCH TO THE CLINIC FOR PEDIATRIC HIGH GRADE GLIOMAS INCLUDING DIFFUSE INTRINSIC PONTINE GLIOMAS.
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- Neuro-Oncology, 2019, v. 21, p. ii68, doi. 10.1093/neuonc/noz036.025
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- Publication type:
- Article
PDTM-12. DLX2 TRANSCRIPTIONAL REGULATION OF CENTRAL NERVOUS SYSTEM CELL FATE RELEVANCE TO PEDIATRIC DIFFUSE MIDLINE GLIOMAS WITH HISTONE 3 MUTATIONS.
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- Neuro-Oncology, 2018, v. 20, p. vi206, doi. 10.1093/neuonc/noy148.854
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- Article
PDTM-16. AN IMPROVED DIFFUSE INTRINSIC PONTINE GLIOMA MODEL INITIATED IN OLIG2-EXPRESSING PROGENITORS OF THE NEONATAL BRAINSTEM.
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- Neuro-Oncology, 2018, v. 20, p. vi207, doi. 10.1093/neuonc/noy148.858
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- Article
Pediatric high-grade glioma: biologically and clinically in need of new thinking.
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- Neuro-Oncology, 2017, v. 19, n. 2, p. 153, doi. 10.1093/neuonc/now101
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- Publication type:
- Article
DETAILED MOLECULAR CHARACTERISATION OF DIFFUSE INTRINSIC PONTINE GLIOMAS IDENTIFIES THREE MOLECULAR SUBGROUPS AND A NOVEL CANCER DRIVER, ACVR1.
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- Neuro-Oncology, 2014, v. 16, n. suppl_3, p. iii26, doi. 10.1093/neuonc/nou208.14
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- Article
ABCG2 AND MDR PROMOTE BRAINSTEM GLIOMAGENESIS AND LIMIT THE EFFICACY OF DASATINIB IN A DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) MOUSE MODEL.
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- Neuro-Oncology, 2014, v. 16, n. suppl_3, p. iii25, doi. 10.1093/neuonc/nou208.8
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- Article
Tumor genotype dictates radiosensitization after Atm deletion in primary brainstem glioma models.
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- 2021
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- Publication type:
- journal article
Large Congenital Melanotic Nevi in an Extremity with Neurocutaneous Melanocytosis.
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- Pediatric Dermatology, 2009, v. 26, n. 1, p. 79, doi. 10.1111/j.1525-1470.2008.00828.x
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- Article
Aurora Kinase B Is a Potential Therapeutic Target in Pediatric Diffuse Intrinsic Pontine Glioma.
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- Brain Pathology, 2013, v. 23, n. 3, p. 244, doi. 10.1111/j.1750-3639.2012.00633.x
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- Article
Novel genetically engineered H3.3G34R model reveals cooperation with ATRX loss in upregulation of Hoxa cluster genes and promotion of neuronal lineage.
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- Neuro-Oncology Advances, 2023, v. 5, n. 1, p. 1, doi. 10.1093/noajnl/vdad003
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- Publication type:
- Article
CDK4/6 and PDGFRA Signaling as Therapeutic Targets in Diffuse intrinsic Pontine Glioma.
- Published in:
- Frontiers in Oncology, 2018, p. 1, doi. 10.3389/fonc.2018.00191
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- Publication type:
- Article
A phase I/Ib trial targeting the Pi3k/Akt pathway using perifosine: Long-term progression-free survival of patients with resistant neuroblastoma.
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- International Journal of Cancer, 2017, v. 140, n. 2, p. 480, doi. 10.1002/ijc.30440
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- Publication type:
- Article
Pre-Clinical Study of Panobinostat in Xenograft and Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma Models.
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- PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0169485
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- Publication type:
- Article
A phase I trial of the CDK 4/6 inhibitor palbociclib in pediatric patients with progressive brain tumors: A Pediatric Brain Tumor Consortium study (PBTC‐042).
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- Pediatric Blood & Cancer, 2021, v. 68, n. 4, p. 1, doi. 10.1002/pbc.28879
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- Publication type:
- Article
A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors.
- Published in:
- 2017
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- Publication type:
- journal article
Genetic and epigenetic instability as an underlying driver of progression and aggressive behavior in IDH-mutant astrocytoma.
- Published in:
- Acta Neuropathologica, 2024, v. 148, n. 1, p. 1, doi. 10.1007/s00401-024-02761-7
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- Article
Histopathological spectrum of paediatric diffuse intrinsic pontine glioma: diagnostic and therapeutic implications.
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- Acta Neuropathologica, 2014, v. 128, n. 4, p. 573, doi. 10.1007/s00401-014-1319-6
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- Publication type:
- Article
IGFBP2 Is Overexpressed by Pediatric Malignant Astrocytomas and Induces the Repair Enzyme DNA-PK.
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- Journal of Child Neurology, 2008, v. 23, n. 10, p. 1205, doi. 10.1177/0883073808321766
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- Publication type:
- Article
Reirradiation for recurrent medulloblastoma.
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- Cancer (0008543X), 2011, v. 117, n. 21, p. 4977, doi. 10.1002/cncr.26148
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- Publication type:
- Article
Tumor location, but not H3.3K27M, significantly influences the blood-brain-barrier permeability in a genetic mouse model of pediatric high-grade glioma.
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- Journal of Neuro-Oncology, 2016, v. 126, n. 2, p. 243, doi. 10.1007/s11060-015-1969-9
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- Publication type:
- Article
A novel mouse model of diffuse midline glioma initiated in neonatal oligodendrocyte progenitor cells highlights cell‐of‐origin dependent effects of H3K27M.
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- Glia, 2022, v. 70, n. 9, p. 1681, doi. 10.1002/glia.24189
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- Publication type:
- Article
The oncolytic adenovirus Delta-24-RGD in combination with ONC201 induces a potent antitumor response in pediatric high-grade and diffuse midline glioma models.
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- Neuro-Oncology, 2024, v. 26, n. 8, p. 1509, doi. 10.1093/neuonc/noae066
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- Article
A new path to alternative lengthening of telomeres?
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- Neuro-Oncology, 2023, v. 25, n. 7, p. 1343, doi. 10.1093/neuonc/noad054
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- Publication type:
- Article