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- Title
Detection of NUDT15 R139C variants and azathioprine utilization in patients with dermatologic conditions.
- Authors
Chung, Kyung B.; Sung, Haejune; Kim, Do‐Young
- Abstract
This article explores the connection between a specific gene variant, NUDT15, and the side effects of thiopurine medication in the Korean population. The study found that a higher percentage of patients had the gene variant than previously reported, and these patients experienced more frequent visits to the dermatology clinic due to side effects. The article emphasizes the need for genetic testing before starting thiopurine therapy, particularly in Eastern populations, and highlights the role of dermatologists in managing hair loss caused by these medications. Additionally, the article discusses the importance of accurate and unbiased information in research, while acknowledging the diverse perspectives within the research community.
- Subjects
AZATHIOPRINE; LEUCOPENIA; ORAL lichen planus; BEHCET'S disease
- Publication
International Journal of Dermatology, 2024, Vol 63, Issue 3, pe75
- ISSN
0011-9059
- Publication type
Article
- DOI
10.1111/ijd.17008