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- Title
ULTRASONICALLY ASSISTED SYNTHESIS OF CHROMEN-2-ONE-1,2,3-TRIAZOLES AND In-vitro ANTICANCER ACTIVITY.
- Authors
Ega, Jagadeesh Kumar; Peddapyata, Prashanth Raja; Siddoju, Kavitha
- Abstract
Synthesis of new series of chromen-2-one-1,2,3-Triazoles (6a-6j) was reported using the help of key methods such as [3+2]-cycloaddition and ultrasound. All compounds were further evaluated for their in vitro anticancer activity profile in three human cancer cell lines MCF-7(breast), A-549 (lungs), and HeLa (cervical). Among all, three compounds namely 6c, 6f, and 6j showed the most promising activity against three lines, when compared with the etoposide.
- Subjects
ANTINEOPLASTIC agents; CELL lines; CANCER cells; ETOPOSIDE; ULTRASONIC imaging
- Publication
Rasayan Journal of Chemistry, 2023, Vol 16, Issue 1, p201
- ISSN
0974-1496
- Publication type
Article
- DOI
10.31788/RJC.2023.1618053