We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The Ontario trial of active compression-decompression cardiopulmonary resuscitation for in-hospital and prehospital cardiac arrest.
- Authors
Stiell IG; Hebert PC; Wells GA; Laupacis A; Vandemheen K; Dreyer JF; Eisenhauer MA; Gibson J; Higginson LAJ; Kirby AS; Mahon JL; Maloney JP; Weitzman BN; Stiell, I G; Hébert, P C; Wells, G A; Laupacis, A; Vandemheen, K; Dreyer, J F; Eisenhauer, M A
- Abstract
<bold>Objective: </bold>To compare the impact of active compression-decompression (ACD) cardiopulmonary resuscitation (CPR) and standard CPR on the outcomes of in-hospital and prehospital victims of cardiac arrest.<bold>Design: </bold>Randomized controlled trial with blinding of allocation using a sealed container.<bold>Settings: </bold>(1) Emergency departments, wards, and intensive care units of 5 university hospitals and (2) all locations outside hospitals in 2 midsized cities.<bold>Patients: </bold>A total of 1784 adults who had cardiac arrest.<bold>Intervention: </bold>Patients received either standard or ACD CPR throughout resuscitation.<bold>Main Outcome Measures: </bold>Survival for 1 hour and to hospital discharge and the modified Mini-Mental State Examination (MMSE).<bold>Results: </bold>All characteristics were similar in the standard and ACD CPR groups for the 773 in-hospital patients and the 1011 prehospital patients. For in-hospital patients, there were no significant differences between the standard (n = 368) and ACD (n = 405) CPR groups in survival for 1 hour (35.1% vs 34.6%; P = .89), in survival until hospital discharge (11.4% vs 10.4%; P = .64), or in the median MMSE score of survivors (37 in both groups). For patients who collapsed outside the hospital, there were also no significant differences between the standard (n = 510) and ACD (n = 501) CPR groups in survival for 1 hour (16.5% vs 18.2%; P = .48), in survival to hospital discharge (3.7% vs 4.6%; P = .49), or in the median MMSE score of survivors (35 in both groups). Exploration of clinically important subgroups failed to identify any patients who appeared to benefit from ACD CPR.<bold>Conclusions: </bold>ACD CPR did not improve survival or neurologic outcomes in any group of patients with cardiac arrest.
- Publication
JAMA: Journal of the American Medical Association, 1996, Vol 275, Issue 18, p1417
- ISSN
0098-7484
- Publication type
journal article
- DOI
10.1001/jama.1996.03530420045034