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- Title
Cats and toxoplasmosis risk in HIV-infected adults.
- Authors
Wallace MR; Rossetti RJ; Olson PE; Wallace, M R; Rossetti, R J; Olson, P E
- Abstract
<bold>Objective: </bold>To establish the prevalence and incidence of toxoplasmosis in an adult human immunodeficiency virus (HIV) population, and to determine if cat ownership contributes to the risk of toxoplasmosis.<bold>Design: </bold>Retrospective record and laboratory review, coupled with a patient survey.<bold>Setting: </bold>A tertiary-care military hospital HIV program.<bold>Patients: </bold>A total of 723 HIV-infected adults, all former or current US military personnel.<bold>Main Outcome Measures: </bold>Prevalence and incidence of serologic evidence of toxoplasmosis infection.<bold>Results: </bold>A total of 723 HIV-infected patients had serial Toxoplasma IgG antibody determinations. Seventy patients (9.7%) were positive on their initial screen; the seronegative patients were tested annually for 1 to 5 years (mean duration of follow-up, 2.1 years). Only 13 patients (2.0%) who were initially seronegative acquired antibodies to Toxoplasma gondii. None of the patients who seroconverted developed clinical disease. A pet history was available on 12 of 13 patients who seroconverted; only one (8.3%) had owned or lived in a household with a cat during the period of seroconversion. The calculated attributable risk of cat ownership/exposure for toxoplasmosis seroconversion in this population is -2.9 per 100 persons annually.<bold>Conclusion: </bold>Toxoplasma antibody seroconversion in an adult HIV-infected population is unusual and appears unrelated to cat ownership or exposure.
- Publication
JAMA: Journal of the American Medical Association, 1993, Vol 269, Issue 1, p76
- ISSN
0098-7484
- Publication type
journal article
- DOI
10.1001/jama.1993.03500010086037