We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Emerging evidence and treatment paradigm of non-small cell lung cancer.
- Authors
Liu, Si-Yang Maggie; Zheng, Mei-Mei; Pan, Yi; Liu, Si-Yang; Li, Yangqiu; Wu, Yi-Long
- Abstract
Research on biomarker-driven therapy and immune check-point blockade in non-small cell lung cancer (NSCLC) is rapidly evolving. The width and depth of clinical trials have also dramatically improved in an unprecedented speed. The personalized treatment paradigm evolved every year. In this review, we summarize the promising agents that have shifted the treatment paradigm for NSCLC patients across all stages, including targeted therapy and immunotherapy using checkpoint inhibitors. Based on recent evidence, we propose treatment algorithms for NSCLC and propose several unsolved clinical issues, which are being explored in ongoing clinical trials. The results of these trials are likely to impact future clinical practice.
- Subjects
NON-small-cell lung carcinoma
- Publication
Journal of Hematology & Oncology, 2023, Vol 16, Issue 1, p1
- ISSN
1756-8722
- Publication type
Article
- DOI
10.1186/s13045-023-01436-2