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- Title
Pathogenesis of renal failure in cirrhosis and fulminant hepatic failure.
- Authors
Wilkinson, S. P.; Hurst, D.; Portmann, B.; Williams, Roger; Williams, R
- Abstract
Acute renal failure in cirrhosis and fulminant hepatic failure represents a spectrum with ‘functional renal failure’ at one end and acute tubular necrosis at the other. In fulminant hepatic failure the development of renal failure is not necessarily a measure of the severity of liver damage. Functional renal failure is due to active renal vasoconstriction which may, at least in fulminant hepatic failure, be initiated by systemic endotoxaemia.
- Subjects
ACUTE kidney failure; BLOOD plasma; BLOOD volume; CARDIAC output; GLOMERULAR filtration rate; HEPATIC encephalopathy; CIRRHOSIS of the liver; DISEASE complications
- Publication
Postgraduate Medical Journal, 1975, Vol 51, Issue 598, p503
- ISSN
0032-5473
- Publication type
journal article