We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
In vitro inhibitory potential of methanolic extract of Celosia argentea var. cristata on tyrosinase, acetylcholinesterase and butyrylcholinesterase enzymes.
- Authors
Saqib, Fatima; Janbaz, Khalid Hussain; Sherwani, Maryam Khan
- Abstract
In the current study, methanol extract of Celosia argentea var. cristata was tested for its inhibitory potential against tyrosinase, acetylcholinesterase and butyrylcholinesterase enzymes at the concentration of 0.5 mM by ELISA microtiter plate assays. A significant tyrosinase inhibitory activity (63.6%), acetylcholinesterase inhibitory activity (80.3%) and butyrylcholinesterse inhibitory activity (68.24%) was shown by crude methanolic extract of C. argentea var. cristata with respective IC50 values of 268.5 ± 0.2 µg/mL, 73.6 ± 0.1 µg/mL and 132.8 ± 0.9 µg/mL. The result of this study reveals the use of C. argentea var. cristata in skin hyperpigmentation, Parkinson's disease and neurodegenerative disorders like Alzheimer's disease and dementia.
- Subjects
IN vitro studies; PLANT extracts; CELOSIA; PLANT metabolism; ACETYLCHOLINESTERASE; PARKINSON'S disease treatment
- Publication
Bangladesh Journal of Pharmacology, 2015, Vol 10, Issue 2, p449
- ISSN
1991-007X
- Publication type
Article
- DOI
10.3329/bjp.v10i2.22880