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- Title
Evaluation of Clinical Outcomes by BMI in Infertile Patients with Assisted Reproduction Treatment:A Meta Analysis.
- Authors
CAO Jing -yun; LI Ai -bin; NIU Ting; SHEN Lan; CHEN Li
- Abstract
Objective: To evaluate the clinical outcomes by BMI in infertile patients with assisted reproductive treatment, so as to guide the reasonable clinical treatment. Methods: We searched CBM,Wanfang, CNKI, VIP,PubMed and FMJS. Those randomized controlled trails(RCTs) or clinical controlled trails(CCT) were identified, which focused on the comparison of clinical outcomes in infertile patients with IVF-ET%ICSI treatment by BMI (between BMI>25 kg/m² and BMI≤25 kg/m²). The duration of search was from January 2000 to June 2014. The extracted data were analyzed by RevMan 5.0. Results: Six literatures with 2 297 cycles were selected for Meta analysis. Meta analysis showed that the pregnancy rate [0R=0.72,95%C/ (0.58,0.90), %=0.004],birth rate [0R=0.65, 95%CI (0.47,0.91), P=0.01] in the high BMI group (BMI>25 kg/m²) were significantly lower than those in the low BMI group(BMI≤25 kg/m²);and the abortion rate [0R=1.70,95%CI(1.23, 2.35),P=0.001] was significantly higher than that in the low BMI group (BMI≤25 kg/m²). There were not significant differences in the incidence of ectopic pregnancy [0R=1.51,95%CI (0.71,3.22), P=0.28] and the cycle cancellation rate [OR=1.06,95%CI (0.70,1.62), P=0.77] between two groups. Conclusions: It is necessary to ask those infertile women with high BMI to control body weight, and to lower BMI before their ART treatment, so as to improve their clinical outcomes of ART treatment.
- Subjects
BODY mass index; FEMALE infertility; HUMAN in vitro fertilization research; INFERTILITY; HUMAN embryo transfer; ECTOPIC pregnancy; PATIENTS; THERAPEUTICS
- Publication
Journal of International Reproductive Health/Family Planning, 2015, Vol 34, Issue 2, p101
- ISSN
1674-1889
- Publication type
Article