We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The Efficacy of Hypertonic Saline Nasal Irrigation for Chronic Sinonasal Symptoms
- Authors
Rabago, David; Pasic, Thomas; Zgierska, Aleksandra; Mundt, Marlon; Barrett, Bruce; Maberry, Rob
- Abstract
Objective: To assess quality of life (QOL) in patients with sinonasal symptoms in response to hypertonic saline nasal irrigation (HSNI), and to assess HSNI use patterns. Study design and setting: The study was an uncontrolled 12-month follow-up to a randomized controlled trial (RCT) and used HSNI in a community setting. We included 54 participants with recurrent or chronic sinonasal symptoms. Forty participants had been in the intervention group of a previous study; 14 had been control participants. Primary outcome measures were the Rhinosinusitis Disability Index (RSDI), a sinus-symptom severity assessment (SIA), and the Sino-Nasal Outcomes Test (SNOT-20). Secondary outcome measures were frequency and pattern of HSNI use, side effects and satisfaction. Results: Among participants using HSNI in the prior RCT, RSDI scores continued to improve, from 73.2 ± 2.6 points to 80.6 ± 2.4 points (P < 0.001). SIA and SNOT-20 scores remained stable. Former control participants reported QOL improvement similar to that of HSNI users in the prior RCT. RSDI scores improved from 62.0 ± 3.9 points to 79.7 ± 3.7 points (P < 0.05), SNOT-20 scores improved from 43.5 ± 5.7 points to 28.4 ± 4.8 points, and SIA scores improved from 4.2 ± 0.3 points to 2.6 ± 0.3 points (P < 0.01). Mean HSNI use for all participants was 2.4 irrigations per week; 33% of participants used HSNI regularly, 55% when symptomatic. Side effects were minor; satisfaction was high. Conclusions: Participants with chronic sinonasal symptoms reported improved QOL and frequent, satisfying use of HSNI. Significance: HSNI is an effective adjunctive treatment of chronic sinonasal symptoms.
- Subjects
SINUSITIS; PARANASAL sinus diseases; NOSE; CHRONIC diseases
- Publication
Otolaryngology-Head & Neck Surgery, 2005, Vol 133, Issue 1, p3
- ISSN
0194-5998
- Publication type
Article
- DOI
10.1016/j.otohns.2005.03.002