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Atorvastatin treatment in a dog preclinical model of Alzheimer's disease leads to up-regulation of haem oxygenase-1 and is associated with reduced oxidative stress in brain.
- Published in:
- International Journal of Neuropsychopharmacology, 2012, v. 15, n. 7, p. 981, doi. 10.1017/S1461145711001118
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- Publication type:
- Article
Oxidative and Nitrosative Modifications of Biliverdin Reductase-A in the Brain of Subjects with Alzheimer's Disease and Amnestic Mild Cognitive Impairment.
- Published in:
- Journal of Alzheimer's Disease, 2011, v. 25, n. 4, p. 623, doi. 10.3233/JAD-2011-110092
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- Publication type:
- Article
Oxidative and nitrosative modifications of biliverdin reductase-A in the brain of subjects with Alzheimer's disease and amnestic mild cognitive impairment.
- Published in:
- 2011
- By:
- Publication type:
- journal article
Identification of a Novel Mechanism Fostering the Alterations of Brain Energy Metabolism: a Link Between AD and T2DM.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.074614
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- Publication type:
- Article
Role of miR‐802 in brain insulin signaling and its impact on Down syndrome.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.074063
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- Publication type:
- Article
Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal‐derived extracellular vesicles.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 8, p. 1498, doi. 10.1002/alz.12499
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- Publication type:
- Article
PERK inhibition promotes the rescue of protein translation and Nrf2‐related antioxidant response: Molecular and cell biology/oxidative stress.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041867
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- Publication type:
- Article
Loss of biliverdin reductase‐a (BVR‐A) impairs beneficial effects of CNS insulin on brain energy metabolism favoring the development of Alzheimer's disease (AD) neuropathology: Impact of CNS insulin signaling in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.039511
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- Publication type:
- Article
High fat diet leads to aberrant protein O‐GlcNAcylation and to the development of Alzheimer disease signatures in mice: Molecular and cell biology/tau.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.039449
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- Publication type:
- Article
Aberrant protein O‐GlcNAcylation drives AD‐like neurodegeneration in DS mice: Molecular and cell biology/others.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.039361
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- Publication type:
- Article
P4‐153: LOSS OF BILIVERDIN REDUCTASE‐A FAVORS TAU HYPER‐PHOSPHORYLATION IN ALZHEIMER DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1333, doi. 10.1016/j.jalz.2019.06.3815
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- Publication type:
- Article
P4‐030: THE EARLY ONSET OF BRAIN INSULIN RESISTANCE IN DOWN SYNDROME: ROLE OF TRIPLICATED MIR802.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1286, doi. 10.1016/j.jalz.2019.06.3689
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- Publication type:
- Article
P3‐179: ABERRANT PERK ACTIVATION IS ASSOCIATED WITH THE DEPLETION OF NRF2 SIGNALING AND THE INCREASE OF OXIDATIVE BURDEN IN DS PATHOLOGY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P999, doi. 10.1016/j.jalz.2019.06.3208
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- Publication type:
- Article
Dynamic Changes of BVRA Protein Levels Occur in Response to Insulin: A Pilot Study in Humans.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 8, p. 7282, doi. 10.3390/ijms24087282
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- Publication type:
- Article
A Bioengineering Strategy to Control ADAM10 Activity in Living Cells.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 2, p. 917, doi. 10.3390/ijms24020917
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- Publication type:
- Article
Role of Biliverdin Reductase A in the Regulation of Insulin Signaling in Metabolic and Neurodegenerative Diseases: An Update.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 10, p. 5574, doi. 10.3390/ijms23105574
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- Publication type:
- Article
High-Fat Diet Leads to Reduced Protein O-GlcNAcylation and Mitochondrial Defects Promoting the Development of Alzheimer's Disease Signatures.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 7, p. 3746, doi. 10.3390/ijms22073746
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- Publication type:
- Article
Reduced Biliverdin Reductase-A Expression in Visceral Adipose Tissue is Associated with Adipocyte Dysfunction and NAFLD in Human Obesity.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 23, p. 9091, doi. 10.3390/ijms21239091
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- Publication type:
- Article
Heme Oxygenase-1 in Central Nervous System Malignancies.
- Published in:
- Journal of Clinical Medicine, 2020, v. 9, n. 5, p. 1562, doi. 10.3390/jcm9051562
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- Publication type:
- Article
BILIVERDIN REDUCTASE-A MEDIATES THE BENEFICIAL EFFECTS OF INTRANASAL INSULIN ADMINISTRATION ON AD PATHOLOGY IN THE BRAIN OF 3XTG-AD MICE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1267, doi. 10.1016/j.jalz.2017.06.1896
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- Publication type:
- Article
ABERRANT POLYUBIQUITOME PROFILE IN DOWN SYNDROME AND ALZHEIMER DISEASE BRAIN.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P995, doi. 10.1016/j.jalz.2017.06.1372
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- Publication type:
- Article
Ferulic acid and its therapeutic potential as a hormetin for age-related diseases.
- Published in:
- Biogerontology, 2009, v. 10, n. 2, p. 97, doi. 10.1007/s10522-008-9160-8
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- Publication type:
- Article
Lack of p53 Affects the Expression of Several Brain Mitochondrial Proteins: Insights from Proteomics into Important Pathways Regulated by p53.
- Published in:
- PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0049846
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- Publication type:
- Article
Basal brain oxidative and nitrative stress levels are finely regulated by the interplay between superoxide dismutase 2 and p53.
- Published in:
- Journal of Neuroscience Research, 2015, v. 93, n. 11, p. 1728, doi. 10.1002/jnr.23627
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- Publication type:
- Article
Increased Mammalian Target of Rapamycin Signaling Contributes to the Accumulation of Protein Oxidative Damage in a Mouse Model of Down's Syndrome.
- Published in:
- Neurodegenerative Diseases, 2016, v. 16, n. 1/2, p. 62, doi. 10.1159/000441419
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- Publication type:
- Article
Down Syndrome Is a Metabolic Disease: Altered Insulin Signaling Mediates Peripheral and Brain Dysfunctions.
- Published in:
- Frontiers in Neuroscience, 2020, v. 14, p. 1, doi. 10.3389/fnins.2020.00670
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- Publication type:
- Article
Characterization of the S-denitrosylating activity of bilirubin.
- Published in:
- Journal of Cellular & Molecular Medicine, 2009, v. 13, n. 8b, p. 2365, doi. 10.1111/j.1582-4934.2008.00680.x
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- Publication type:
- Article
Exosomal-miRNas expression and growth factors released by mononuclear cells of CLAD patients in response to extracorporeal photopheresis.
- Published in:
- Journal of Translational Medicine, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12967-024-05045-6
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- Publication type:
- Article
Sex differences in brain proteomes of neuron-specific STAT3-null mice after cerebral ischemia/reperfusion.
- Published in:
- Journal of Neurochemistry, 2012, v. 121, n. 4, p. 680, doi. 10.1111/j.1471-4159.2012.07721.x
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- Publication type:
- Article
Biliverdin reductase-A: a novel drug target for atorvastatin in a dog pre-clinical model of Alzheimer disease.
- Published in:
- Journal of Neurochemistry, 2012, v. 120, n. 1, p. 135, doi. 10.1111/j.1471-4159.2011.07538.x
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- Publication type:
- Article
The protective role of carotenoids against 7-keto-cholesterol formation in solution.
- Published in:
- Molecular & Cellular Biochemistry, 2008, v. 309, n. 1/2, p. 61, doi. 10.1007/s11010-007-9643-y
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- Publication type:
- Article
Altered Brain Cholesterol Machinery in a Down Syndrome Mouse Model: A Possible Common Feature with Alzheimer's Disease.
- Published in:
- Antioxidants, 2024, v. 13, n. 4, p. 435, doi. 10.3390/antiox13040435
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- Publication type:
- Article
Intranasal Administration of KYCCSRK Peptide Rescues Brain Insulin Signaling Activation and Reduces Alzheimer's Disease-like Neuropathology in a Mouse Model for Down Syndrome.
- Published in:
- Antioxidants, 2023, v. 12, n. 1, p. 111, doi. 10.3390/antiox12010111
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- Publication type:
- Article
Native α-Synuclein, 3-Nitrotyrosine Proteins, and Patterns of Nitro-α-Synuclein-Immunoreactive Inclusions in Saliva and Submandibulary Gland in Parkinson's Disease.
- Published in:
- Antioxidants, 2021, v. 10, n. 5, p. 715, doi. 10.3390/antiox10050715
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- Publication type:
- Article
Regulation of Mitochondrial Dynamics in Parkinson's Disease—Is 2-Methoxyestradiol a Missing Piece?
- Published in:
- Antioxidants, 2021, v. 10, n. 2, p. 248, doi. 10.3390/antiox10020248
- By:
- Publication type:
- Article
Proteomics Study of Peripheral Blood Mononuclear Cells in Down Syndrome Children.
- Published in:
- Antioxidants, 2020, v. 9, n. 11, p. 1112, doi. 10.3390/antiox9111112
- By:
- Publication type:
- Article
The BACH1/Nrf2 Axis in Brain in Down Syndrome and Transition to Alzheimer Disease-Like Neuropathology and Dementia.
- Published in:
- Antioxidants, 2020, v. 9, n. 9, p. 779, doi. 10.3390/antiox9090779
- By:
- Publication type:
- Article
BVR-A Deficiency Leads to Autophagy Impairment through the Dysregulation of AMPK/mTOR Axis in the Brain—Implications for Neurodegeneration.
- Published in:
- Antioxidants, 2020, v. 9, n. 8, p. 671, doi. 10.3390/antiox9080671
- By:
- Publication type:
- Article
Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling.
- Published in:
- Science Signaling, 2022, v. 15, n. 733, p. 1, doi. 10.1126/scisignal.abh3066
- By:
- Publication type:
- Article
It Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and UCHL1 in Alzheimer Disease.
- Published in:
- Oxidative Medicine & Cellular Longevity, 2016, p. 1, doi. 10.1155/2016/2756068
- By:
- Publication type:
- Article
Valorization of Tomato Waste as a Source of Carotenoids.
- Published in:
- Molecules, 2021, v. 26, n. 16, p. 5062, doi. 10.3390/molecules26165062
- By:
- Publication type:
- Article
Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse model of Down syndrome.
- Published in:
- Translational Neurodegeneration, 2018, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40035-018-0133-9
- By:
- Publication type:
- Article
Biliverdin Reductase-A correlates with inducible nitric oxide synthasein in atorvastatin treated aged canine brain.
- Published in:
- Neural Regeneration Research, 2013, v. 8, n. 21, p. 1925, doi. 10.3969/j.issn.1673-5374.2013.21.001
- By:
- Publication type:
- Article
Biliverdin Reductase-A Mediates the Beneficial Effects of Intranasal Insulin in Alzheimer Disease.
- Published in:
- Molecular Neurobiology, 2019, v. 56, n. 4, p. 2922, doi. 10.1007/s12035-018-1231-5
- By:
- Publication type:
- Article
Editorial: Brain Insulin Resistance in Neurodevelopmental and Neurodegenerative Disorders: Mind the Gap!
- Published in:
- 2021
- By:
- Publication type:
- Editorial