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- Title
Magnetic resonance imaging in pantothenate kinase-2-associated neurodegeneration.
- Authors
Singh, Paramdeep; Saggar, Kavita; Kaur, Maneet; Pannu, Davinder Singh
- Abstract
Pantothenate kinase-2-associated neurodegeneration (PKAN) is a rare autosomal recessive pediatric neurodegenerative disorder characterized by rigidity, dystonia, impaired postural reflexes, and progressive dementia. On T2-weighted magnetic resonance imaging images, marked low signal intensity is seen in the globus pallidus. This low signal intensity surrounds a central region of high signal intensity in the anteromedial globus pallidus, giving an eye-of-the-tiger appearance.
- Subjects
GENETIC disorder diagnosis; NEURODEGENERATION; DEMENTIA; DYSTONIA; MAGNETIC resonance imaging; PANTOTHENIC acid; DIAGNOSIS
- Publication
Journal of Pediatric Neurosciences, 2012, Vol 7, Issue 1, p27
- ISSN
1817-1745
- Publication type
Article
- DOI
10.4103/1817-1745.97618