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- Title
Severe Anti-epileptic Drug-induced Gingival Overgrowth in a Physically Disabled Patient.
- Authors
Kaomongkolgit, R.; Tantanapornkul, W.; Jittapiromsak, N.; Ngamwannagul, P.; Sriaroon, P.
- Abstract
Anti-epileptic drugs are considered to be the main drugs associated with gingival overgrowth. The coadministration of phenytoin and other anti-epileptic drugs, which increases the risk of phenytoininduced gingival overgrowth, has been previously reported. However, no report has been done considering the new generation of anti-epileptic drug topiramate and its association with gingival overgrowth. High levels of dental plaque and calculus have also been reported as being a critical risk factor in the development and severity of drug-induced gingival overgrowth. Thus, this case report highlights the occurrence of severe gingival overgrowth and generalized periodontitis in a physically disabled patient with epilepsy who had been taking phenytoin and topiramate drugs for 10 years. It also emphasizes the importance for both medical and dental professionals to reduce the severity and impact of drug-induced gingival overgrowth.
- Subjects
ANTICONVULSANTS; GINGIVAL hyperplasia; PHENYTOIN; TOPIRAMATE; PEOPLE with disabilities; PEOPLE with epilepsy
- Publication
West Indian Medical Journal, 2016, Vol 65, Issue 1, p212
- ISSN
0043-3144
- Publication type
Article
- DOI
10.7727/wimj.2014.359