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- Title
Prevalence of vitamin A and vitamin D deficiency in hospitalized neonates in Xi'an, China.
- Authors
Ruiping Liu; Haibin Wu; Yang Chen; Fengmei Xiong; Jiangang Zhao; Huan Sun; Yuanyuan Li; Fangyuan He; Liu, Ruiping; Wu, Haibin; Chen, Yang; Xiong, Fengmei; Zhao, Jiangang; Sun, Huan; Li, Yuanyuan; He, Fangyuan
- Abstract
<bold>Background and Objectives: </bold>To investigate the prevalence of vitamin A and vitamin D deficiency and the associated factors in hospitalized neonates in Xi'an, China.<bold>Methods and Study Design: </bold>A total of 524 hospitalized neonates were collected in this study. Serum vitamin A and D concentrations were detected in neonates within two weeks of birth.<bold>Results: </bold>Serum vitamin A and D concentrations of hospitalized neonates were 0.55±0.21 μmol/L and 42.0±20.6 nmol/L, respectively. They were greater in full-term neonates than in preterm neonates, greater in rural neonates than in urban, and greater in single than in twin (all p<0.001). The prevalence of vitamin A and D deficiency were 14.9% and 33.0%, the prevalence of marginal vitamin A deficiency was 64.7%, and vitamin D insufficiency was 35.1%. Neonatal serum vitamin A and D concentrations were all positively correlated with birth weight and gestational age. Neonatal serum vitamin D concentration was also positively correlated with maternal serum vitamin D concentration. Additionally, neonatal vitamin A concentration was positively correlated with neonatal serum vitamin D concentration.<bold>Conclusions: </bold>Vitamin A and vitamin D statuses are compromised in hospitalized neonates in Xi'an, especially in premature neonates, low birth weight neonates, twins, and those born in urban areas. Individualized supplementation with vitamin A and vitamin D in neonates should be a clinical consideration.
- Subjects
VITAMINS; VITAMIN A deficiency; VITAMIN D; VITAMIN A; DISEASE prevalence; VITAMIN D deficiency
- Publication
Asia Pacific Journal of Clinical Nutrition, 2022, Vol 31, Issue 2, p275
- ISSN
0964-7058
- Publication type
journal article
- DOI
10.6133/apjcn.202206_31(2).0013