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- Title
Alkyl ammonium hydrogen sulfate immobilized on Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticles: a highly efficient catalyst for the multi-component preparation of novel tetrazolo[1,5-a]pyrimidine-6-carboxamide derivatives.
- Authors
Khalaj, Mehdi; Musavi, Seyed Mahmoud; Ghashang, Majid
- Abstract
In this, a three-component reaction for the preparation of novel tetrazolo[1,5-a]pyrimidine-6-carboxamide derivatives from N,N′-(sulfonylbis(1,4-phenylene))bis(3-oxobutanamide), aldehydes and 1H-tetrazol-5-amine is reported. The application of Fe3O4@SiO2-(PP)(HSO4)2 (A) as a catalyst afforded the desired products (a1–a18) in high yields in DMF as solvent as well as under solvent-free conditions.
- Subjects
SULFURIC acid; AMMONIUM sulfate; CATALYSTS; NANOPARTICLES; HETEROGENEOUS catalysts
- Publication
Scientific Reports, 2024, Vol 14, Issue 1, p1
- ISSN
2045-2322
- Publication type
Article
- DOI
10.1038/s41598-024-59096-2