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- Title
CT colonography with minimal bowel preparation: evaluation of tagging quality, patient acceptance and diagnostic accuracy in two iodine-based preparation schemes.
- Authors
Liedenbaum MH; de Vries AH; Gouw CI; van Rijn AF; Bipat S; Dekker E; Stoker J; Liedenbaum, Marjolein H; de Vries, A H; Gouw, C I B F; van Rijn, A F; Bipat, S; Dekker, E; Stoker, J
- Abstract
<bold>Purpose: </bold>The aim of this study was to compare a 1-day with a 2-day iodine bowel preparation for CT colonography in a positive faecal occult blood test (FOBT) screening population.<bold>Materials and Methods: </bold>One hundred consecutive patients underwent CT colonography and colonoscopy with segmental unblinding. The first 50 patients (group 1) ingested 7 50 ml iodinated contrast starting 2 days before CT colonography. The latter 50 patients (group 2) ingested 4 50 ml iodinated contrast starting 1 day before CT colonography. Per colonic segment measurements of residual stool attenuation and homogeneity were performed, and a subjective evaluation of tagging quality (grade 1-5) was done. Independently, two reviewers performed polyp and carcinoma detection.<bold>Results: </bold>The tagging density was 638 and 618 HU (p = 0.458) and homogeneity 91 and 86 HU for groups 1 and 2, respectively (p = 0.145). The tagging quality was graded 5 (excellent) in 90% of all segments in group 1 and 91% in group 2 (p = 0.749). Mean per-polyp sensitivity for lesions >or=10 mm was 86% in group 1 and 97% in group 2 (p = 0.355). Patient burden from diarrhoea significantly decreased for patients in group 2.<bold>Conclusions: </bold>One-day preparation with meglumine ioxithalamate results in an improved patient acceptability compared with 2-day preparation and has a comparable, excellent image quality and good diagnostic performance.
- Publication
European Radiology, 2010, Vol 20, Issue 2, p367
- ISSN
0938-7994
- Publication type
journal article
- DOI
10.1007/s00330-009-1570-8