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- Title
Pharmacokinetic interaction between maraviroc and etravirine in HIV-infected patients receiving regimens containing both drugs and no ritonavir-boosted protease inhibitor.
- Authors
Lê, Minh Patrick; Solas, Caroline; Garraffo, Rodolphe; Gagnieu, Marie-Claude; Muret, Patrice; Yeni, Patrick; Dhiver, Catherine; Katlama, Christine; Poizot-Martin, Isabelle; Durant, Jacques; Peytavin, Gilles
- Abstract
The article examines pharmacokinetic interaction between maraviroc and etravirine in patients with human immunodeficiency virus (HIV). It highlights the use of ritonavir to counteract the etravirine inducer effects on maraviroc metabolism which could be cost-effective alternative to higher maraviroc doses. It also mentions the importance of routine therapeutic drug monitoring.
- Subjects
PHARMACOKINETICS; MARAVIROC (Drug); ETRAVIRINE (Drug); HIV-positive persons; DRUG monitoring
- Publication
Journal of Antimicrobial Chemotherapy (JAC), 2012, Vol 67, Issue 11, p2779
- ISSN
0305-7453
- Publication type
Article